FungiFlex®
Mold Panel
Detects fungal cell-free DNA in plasma to identify invasive mold infections direct from plasma
Results Reported
14 species of molds reported in 7 clinically actionable groups
Clinical Utility
A plasma-based mold cfDNA assay offers a rapid, noninvasive way to support the diagnosis of invasive fungal infection — without biopsy or bronchoalveolar lavage.
Invasive fungal infections can present as a range of syndromes, including invasive rhinosinusitis, pneumonia, central nervous system disease, and skin or soft tissue involvement. As the number of patients undergoing transplantation and receiving immunosuppressive therapy continues to grow, so does the at-risk population and the incidence of IFIs. Aspergillus species and Mucorales are among the most frequent causes, and are usually diagnosed by sampling deep tissues such as lung — often through biopsy, or by bronchoalveolar lavage (BAL) as a less invasive surrogate. Both approaches carry procedural risk and may be nondiagnostic when paired with conventional assays.
Specimen Instructions
Sample requirements
- Whole Blood If received by the Zepto laboratory < 24 hours after collection
- Plasma If received by the Zepto laboratory > 24 hours after collection
Sample stability
| Sample type | Temperature | Stability |
|---|---|---|
| Whole Blood | Ambient | Up to 24 hours |
| Plasma | Ambient | Up to 96 hours |
| Frozen Plasma | ≤ −20°C | Up to 6 months |
Storage & shipping
-
Store plasma at ambient temperature (4–25°C) for short-term holding.
-
Specimens must arrive at Zepto Life within 96 hours of blood draw when shipped at ambient temperature.
-
If shipment will be delayed beyond 96 hours, freeze plasma at ≤ −20°C and ship on dry ice.
-
Frozen specimens may be stored at ≤ −20°C for up to 6 months prior to shipment.